Department of Dermatology, Venereology and Allergology, Clinical Research Division University Hospital Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Department for Prevention and Care of Diabetes, Medical Faculty Carl Gustav Carus, Technical University of Dresden, 01062 Dresden, Germany. Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital and Faculty of Medicine, 01307 Dresden, Germany. German Center for Diabetes Research, 85764 Neuherberg, Germany. Psoriasis-Center, Department of Dermatology, Campus Kiel, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany. Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, 04103 Leipzig, Germany. Novartis Pharma AG, 4056 Basel, Switzerland. Novartis Pharma GmbH, 90429 Nuremberg, Germany.